Opioid overdose has long been a leading cause of death, especially among Americans under 50. The current “4th wave” of the epidemic—marked by potent fentanyl analogues, stimulant co-use, and contamination with substances like xylazine—makes treatment increasingly difficult. While evidence-based tools like buprenorphine, methadone, naloxone, and harm reduction remain essential, access is often blocked by insurance issues, stigma, transportation, and provider shortages. As a result, first responders and EMS, already stretched thin, bear much of the burden.

Post-Overdose Response Teams (PORT) offer a promising solution—delivering evidence-based care directly in the field and reducing both risk and system strain. These teams can be effective in any setting by collaborating with providers, public health, law enforcement, and harm reduction programs. This training will explore the current opioid crisis, addiction science, medication treatment, and how to build a PORT program—from assessing needs to forming partnerships, establishing protocols, and tracking outcomes.